Ivermectin treatment of Loa loa hyper-microfilaraemic baboons (Papio anubis): Assessment of microfilarial load reduction, haematological and biochemical parameters and histopathological changes following treatment

BACKGROUND: Individuals with high intensity of Loa loa are at risk of developing serious adverse events (SAEs) post treatment with ivermectin. These SAEs have remained unclear and a programmatic impediment to the advancement of community directed treatment with ivermectin. The pathogenesis of these...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Wanji, Samuel, Eyong, Ebanga-Echi J., Tendongfor, Nicholas, Ngwa, Che J., Esuka, Elive N., Kengne-Ouafo, Arnaud J., Datchoua-Poutcheu, Fabrice R., Enyong, Peter, Agnew, Dalen, Eversole, Rob R., Hopkins, Adrian, Mackenzie, Charles D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533442/
https://ncbi.nlm.nih.gov/pubmed/28686693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005576
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