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Modulation of kanamycin B and kanamycin A biosynthesis in Streptomyces kanamyceticus via metabolic engineering

Both kanamycin A and kanamycin B, antibiotic components produced by Streptomyces kanamyceticus, have medical value. Two different pathways for kanamycin biosynthesis have been reported by two research groups. In this study, to obtain an optimal kanamycin A-producing strain and a kanamycin B-high-yie...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Gao, Wenli, Wu, Zheng, Sun, Junyang, Ni, Xianpu, Xia, Huanzhang
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533434/
https://ncbi.nlm.nih.gov/pubmed/28753625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181971
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