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Inactivation of liver X receptor β leads to adult-onset motor neuron degeneration in male mice
Male mice with inactivated liver X receptor (LXR) β suffer from adult-onset motor neuron degeneration. By 7 months of age, motor coordination is impaired, and this condition is associated with lipid accumulation and loss of motor neurons in the spinal cord, together with axonal atrophy and astroglio...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC553330/ https://ncbi.nlm.nih.gov/pubmed/15738425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500634102 |
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