The MicroRNA-199a/214 Cluster Targets E-Cadherin and Claudin-2 and Promotes High Glucose-Induced Peritoneal Fibrosis

Serum response factor (SRF) was found to be involved in the phenotypic transition and fibrosis of the peritoneal membrane during treatment with peritoneal dialysis (PD), but the exact mechanism remains unclear. SRF regulates microRNAs (miRNAs) that contain the SRF-binding consensus (CArG) element in...

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Bibliographic Details
Published in:J Am Soc Nephrol
Main Authors: Che, Mingwen, Shi, Tiantian, Feng, Shidong, Li, Huan, Zhang, Xiaomin, Feng, Ning, Lou, Weijuan, Dou, Jianhua, Tang, Guangbo, Huang, Chen, Xu, Guoshuang, Qian, Qi, Sun, Shiren, He, Lijie, Wang, Hanmin
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2017
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533225/
https://ncbi.nlm.nih.gov/pubmed/28428333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016060663
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