The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability

By meta-analyzing rare coding variants in whole-exome sequences of 4,133 schizophrenia cases and 9,274 controls, de novo mutations in 1,077 trios, and copy number variants from 6,882 cases and 11,255 controls, we show that individuals with schizophrenia carry a significant burden of rare damaging va...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Singh, Tarjinder, Walters, James T. R., Johnstone, Mandy, Curtis, David, Suvisaari, Jaana, Torniainen, Minna, Rees, Elliott, Iyegbe, Conrad, Blackwood, Douglas, McIntosh, Andrew M., Kirov, Georg, Geschwind, Daniel, Murray, Robin M., Di Forti, Marta, Bramon, Elvira, Gandal, Michael, Hultman, Christina M., Sklar, Pamela, Palotie, Aarno, Sullivan, Patrick F., O'Donovan, Michael C., Owen, Michael J., Barrett, Jeffrey C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533219/
https://ncbi.nlm.nih.gov/pubmed/28650482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3903
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados