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Stochastic Modeling Yields a Mechanistic Framework for Spindle Attachment Error Correction in Budding Yeast Mitosis

Proper segregation of the replicated genome requires that kinetochores form and maintain bi-oriented, amphitelic attachments to microtubules from opposite spindle poles and eliminate erroneous, syntelic attachments to microtubules from the same spindle pole. Phosphorylation of kinetochore proteins d...

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Publicat a:Cell Syst
Autors principals: Tubman, Emily S., Biggins, Sue, Odde, David J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533192/
https://ncbi.nlm.nih.gov/pubmed/28601560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.05.003
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