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Proton binding within a membrane protein by a protonated water cluster

Proton transfer is crucial for many enzyme reactions. Here, we show that in addition to protonatable amino acid side chains, water networks could constitute proton-binding sites in proteins. A broad IR continuum absorbance change during the proton pumping photocycle of bacteriorhodopsin (bR) indicat...

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Bibliografische gegevens
Hoofdauteurs: Garczarek, Florian, Brown, Leonid S., Lanyi, Janos K., Gerwert, Klaus
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC553315/
https://ncbi.nlm.nih.gov/pubmed/15738416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500421102
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