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HLA-restricted epitope identification and detection of functional T cell responses by using MHC–peptide and costimulatory microarrays

Identification of T cell epitopes is a vital but often slow and difficult step in studying the immune response to infectious agents and autoantigens. We report a spatially addressable technique for screening large numbers of T cell epitopes for both specific antigen recognition and functional activi...

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Detalhes bibliográficos
Main Authors: Stone, Jennifer D., Demkowicz, Walter E., Stern, Lawrence J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC553304/
https://ncbi.nlm.nih.gov/pubmed/15728728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407019102
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