Use of p53‐Silenced Endothelial Progenitor Cells to Treat Ischemia in Diabetic Peripheral Vascular Disease

BACKGROUND: Peripheral vascular disease is a major diabetes mellitus‐related complication. In this study, we noted that expressions of proapoptotic p53 gene and its downstream cascade gene such as p21 are upregulated in hyperglycemia. Therefore, we investigated whether p53‐ and p21‐silenced endothel...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Kundu, Nabanita, Domingues, Cleyton C., Chou, Cyril, Ahmadi, Neeki, Houston, Sara, Jerry, D. Joseph, Sen, Sabyasachi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533015/
https://ncbi.nlm.nih.gov/pubmed/28365567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.005146
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