Intracellular Angiotensin‐II Interacts With Nuclear Angiotensin Receptors in Cardiac Fibroblasts and Regulates RNA Synthesis, Cell Proliferation, and Collagen Secretion

BACKGROUND: Cardiac fibroblasts play important functional and pathophysiological roles. Intracellular (“intracrine”) angiotensin‐II (Ang‐II) signaling regulates intercellular communication, excitability, and gene expression in cardiomyocytes; however, the existence and role of intracrine Ang‐II sign...

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Vydáno v:J Am Heart Assoc
Hlavní autoři: Tadevosyan, Artavazd, Xiao, Jiening, Surinkaew, Sirirat, Naud, Patrice, Merlen, Clémence, Harada, Masahide, Qi, Xiaoyan, Chatenet, David, Fournier, Alain, Allen, Bruce G., Nattel, Stanley
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533010/
https://ncbi.nlm.nih.gov/pubmed/28381466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004965
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