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SIRT3: Oncogene and Tumor Suppressor in Cancer
Sirtuin 3 (SIRT3), the major deacetylase in mitochondria, plays a crucial role in modulating oxygen reactive species (ROS) and limiting the oxidative damage in cellular components. SIRT3 targets different enzymes which regulate mitochondrial metabolism and participate in ROS detoxification, such as...
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| Pubblicato in: | Cancers (Basel) |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5532626/ https://ncbi.nlm.nih.gov/pubmed/28704962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9070090 |
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