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Cell number and chondrogenesis in human mesenchymal stem cell aggregates is affected by the sulfation level of heparin used as a cell coating

For particular cell-based therapies, it may be required to culture mesenchymal stem cell (MSC) aggregates with growth factors to promote cell proliferation and/or differentiation. Heparin, a negatively charged glycosaminoglycan (GAG) is known to play an important role in sequestration of positively...

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Detalhes bibliográficos
Publicado no:J Biomed Mater Res A
Main Authors: Lei, Jennifer, Trevino, Elda, Temenoff, Johnna
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532474/
https://ncbi.nlm.nih.gov/pubmed/26990913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.35713
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