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Lessons Learned about Neurodegeneration from Microglia and Monocyte Depletion Studies

While bone marrow-derived Ly6C(hi) monocytes can infiltrate the central nervous system (CNS) they are developmentally and functionally distinct from resident microglia. Our understanding of the relative importance of these two populations in the distinct processes of pathogenesis and resolution of i...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Lund, Harald, Pieber, Melanie, Harris, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532389/
https://ncbi.nlm.nih.gov/pubmed/28804456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00234
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