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Honokiol suppresses formyl peptide-induced human neutrophil activation by blocking formyl peptide receptor 1
Formyl peptide receptor 1 (FPR1) mediates bacterial and mitochondrial N-formyl peptides-induced neutrophil activation. Therefore, FPR1 is an important therapeutic target for drugs to treat septic or sterile inflammatory diseases. Honokiol, a major bioactive compound of Magnoliaceae plants, possesses...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5532207/ https://ncbi.nlm.nih.gov/pubmed/28751674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07131-w |
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