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A single nucleotide polymorphism causes enhanced radical oxygen species production by human aldehyde oxidase

Aldehyde oxidases (AOXs) are molybdo-flavoenzymes characterized by broad substrate specificity, oxidizing aromatic/aliphatic aldehydes into the corresponding carboxylic acids and hydroxylating various heteroaromatic rings. The enzymes use oxygen as the terminal electron acceptor and produce reduced...

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Publicat a:PLoS One
Autors principals: Foti, Alessandro, Dorendorf, Frank, Leimkühler, Silke
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531472/
https://ncbi.nlm.nih.gov/pubmed/28750088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182061
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