Lymphocytes transiently expressing virus-specific T cell receptors reduce hepatitis B virus infection

Adoptive transfer of T cells engineered to express a hepatitis B virus–specific (HBV-specific) T cell receptor (TCR) may supplement HBV-specific immune responses in chronic HBV patients and facilitate HBV control. However, the risk of triggering unrestrained proliferation of permanently engineered T...

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Publicado en:J Clin Invest
Autores principales: Kah, Janine, Koh, Sarene, Volz, Tassilo, Ceccarello, Erica, Allweiss, Lena, Lütgehetmann, Marc, Bertoletti, Antonio, Dandri, Maura
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531408/
https://ncbi.nlm.nih.gov/pubmed/28737510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI93024
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