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B-1a Cells Protect Mice from Sepsis: Critical Role of cAMP-response Element Binding Protein (CREB)

Bacterial sepsis is a serious life-threatening condition caused by an excessive immune response to infection. B-1 cells differ from conventional B-2 cells by their distinct phenotype and function. A subset of B-1 cells expressing CD5, known as B-1a cells, exhibits innate immune activity. Here we rep...

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Vydáno v:J Immunol
Hlavní autoři: Aziz, Monowar, Holodick, Nichol E., Rothstein, Thomas L., Wang, Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531203/
https://ncbi.nlm.nih.gov/pubmed/28630091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1602056
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