Western Diet–Induced Dysbiosis in Farnesoid X Receptor Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment

Patients who have liver cirrhosis and liver cancer also have reduced farnesoid X receptor (FXR). The current study analyzes the effect of diet through microbiota that affect hepatic inflammation in FXR knockout (KO) mice. Wild-type and FXR KO mice were on a control (CD) or Western diet (WD) for 10 m...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Jena, Prasant K., Sheng, Lili, Liu, Hui-Xin, Kalanetra, Karen M., Mirsoian, Annie, Murphy, William J., French, Samuel W., Krishnan, Viswanathan V., Mills, David A., Wan, Yu-Jui Yvonne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530909/
https://ncbi.nlm.nih.gov/pubmed/28711154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.04.019
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