Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses

The recent development of immunotherapy as a cancer treatment has proved effective over recent years, but the precise dynamics between the tumor microenvironment (TME), nontumor microenvironment (NTME), and the systemic immune system remain elusive. Here, we interrogated these compartments in hepato...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Chew, Valerie, Lai, Liyun, Pan, Lu, Lim, Chun Jye, Li, Juntao, Ong, Raymond, Chua, Camillus, Leong, Jing Yao, Lim, Kiat Hon, Toh, Han Chong, Lee, Ser Yee, Chan, Chung Yip, Goh, Brian K. P., Chung, Alexander, Chow, Pierce K. H., Albani, Salvatore
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530700/
https://ncbi.nlm.nih.gov/pubmed/28674001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706559114
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