Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses

The recent development of immunotherapy as a cancer treatment has proved effective over recent years, but the precise dynamics between the tumor microenvironment (TME), nontumor microenvironment (NTME), and the systemic immune system remain elusive. Here, we interrogated these compartments in hepato...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Chew, Valerie, Lai, Liyun, Pan, Lu, Lim, Chun Jye, Li, Juntao, Ong, Raymond, Chua, Camillus, Leong, Jing Yao, Lim, Kiat Hon, Toh, Han Chong, Lee, Ser Yee, Chan, Chung Yip, Goh, Brian K. P., Chung, Alexander, Chow, Pierce K. H., Albani, Salvatore
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2017
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530700/
https://ncbi.nlm.nih.gov/pubmed/28674001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706559114
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