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Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses

The recent development of immunotherapy as a cancer treatment has proved effective over recent years, but the precise dynamics between the tumor microenvironment (TME), nontumor microenvironment (NTME), and the systemic immune system remain elusive. Here, we interrogated these compartments in hepato...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chew, Valerie, Lai, Liyun, Pan, Lu, Lim, Chun Jye, Li, Juntao, Ong, Raymond, Chua, Camillus, Leong, Jing Yao, Lim, Kiat Hon, Toh, Han Chong, Lee, Ser Yee, Chan, Chung Yip, Goh, Brian K. P., Chung, Alexander, Chow, Pierce K. H., Albani, Salvatore
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530700/
https://ncbi.nlm.nih.gov/pubmed/28674001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706559114
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