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Genome sequence of a diabetes-prone rodent reveals a mutation hotspot around the ParaHox gene cluster

The sand rat Psammomys obesus is a gerbil species native to deserts of North Africa and the Middle East, and is constrained in its ecology because high carbohydrate diets induce obesity and type II diabetes that, in extreme cases, can lead to pancreatic failure and death. We report the sequencing of...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Hargreaves, Adam D., Zhou, Long, Christensen, Josef, Marlétaz, Ferdinand, Liu, Shiping, Li, Fang, Jansen, Peter Gildsig, Spiga, Enrico, Hansen, Matilde Thye, Pedersen, Signe Vendelbo Horn, Biswas, Shameek, Serikawa, Kyle, Fox, Brian A., Taylor, William R., Mulley, John Frederick, Zhang, Guojie, Heller, R. Scott, Holland, Peter W. H.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530673/
https://ncbi.nlm.nih.gov/pubmed/28674003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702930114
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