Alterations in Gray Matter Volume are Associated with Reduced Evoked-Pain Connectivity following Acute Pregabalin Administration

OBJECTIVE; Pregabalin (PGB) is an α2β calcium channel subunit ligand that has previously been shown to reduce chronic pain in multiple conditions. Preclinical studies indicate that PGB may down-regulate brain glutamate release while also inhibiting astrocyte induction of glutamatergic synapse format...

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Foilsithe in:Arthritis Rheumatol
Main Authors: Puiu, Tudor, Kairys, Anson E., Pauer, Lynne, Schmidt-Wilcke, Tobias, Ichesco, Eric, Hampson, Johnson P., Napadow, Vitaly, Clauw, Daniel J., Harris, Richard E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530584/
https://ncbi.nlm.nih.gov/pubmed/26816332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39600
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