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Disrupted Skeletal Muscle Mitochondrial Dynamics, Mitophagy, and Biogenesis during Cancer Cachexia: A Role for Inflammation

Chronic inflammation is a hallmark of cancer cachexia in both patients and preclinical models. Cachexia is prevalent in roughly 80% of cancer patients and accounts for up to 20% of all cancer-related deaths. Proinflammatory cytokines IL-6, TNF-α, and TGF-β have been widely examined for their regulat...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Principais autores: VanderVeen, Brandon N., Fix, Dennis K., Carson, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530417/
https://ncbi.nlm.nih.gov/pubmed/28785374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3292087
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