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Only minor differences in renal osteodystrophy features between wild-type and sclerostin knockout mice with chronic kidney disease

Renal osteodystrophy affects the majority of patients with advanced chronic kidney disease (CKD) and is characterized by progressive bone loss. This study evaluated the effects of sclerostin knockout on bone in a murine model of severe, surgically induced CKD in both sclerostin knockout and wild-typ...

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Bibliographic Details
Published in:Kidney Int
Main Authors: Cejka, Daniel, Parada-Rodriguez, Diego, Pichler, Stefanie, Marculescu, Rodrig, Kramer, Ina, Kneissel, Michaela, Gross, Thomas, Reisinger, Andreas, Pahr, Dieter, Monier-Faugere, Marie-Claude, Haas, Martin, Malluche, Hartmut H.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530366/
https://ncbi.nlm.nih.gov/pubmed/27528549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.06.019
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