Carbamylation of vimentin is inducible by smoking and represents an independent autoantigen in rheumatoid arthritis

OBJECTIVES: Smoking has been connected to citrullination of antigens and formation of anti-citrullinated peptide antibodies (ACPAs) in rheumatoid arthritis (RA). Since smoking can modify proteins by carbamylation (formation of homocitrulline), this study was conducted to investigate these effects on...

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Dettagli Bibliografici
Pubblicato in:Ann Rheum Dis
Autori principali: Ospelt, Caroline, Bang, Holger, Feist, Eugen, Camici, Giovanni, Keller, Stephan, Detert, Jacqueline, Krämer, Anette, Gay, Steffen, Ghannam, Khetam, Burmester, Gerd R
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2017
Soggetti:
Clinical and Epidemiological Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530349/
https://ncbi.nlm.nih.gov/pubmed/28183721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2016-210059
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