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Efficacy and safety of sarilumab monotherapy versus adalimumab monotherapy for the treatment of patients with active rheumatoid arthritis (MONARCH): a randomised, double-blind, parallel-group phase III trial

OBJECTIVES: To compare efficacy and safety of sarilumab monotherapy with adalimumab monotherapy in patients with active rheumatoid arthritis (RA) who should not continue treatment with methotrexate (MTX) due to intolerance or inadequate response. METHODS: MONARCH was a randomised, active-controlled,...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Burmester, Gerd R, Lin, Yong, Patel, Rahul, van Adelsberg, Janet, Mangan, Erin K, Graham, Neil M H, van Hoogstraten, Hubert, Bauer, Deborah, Ignacio Vargas, Juan, Lee, Eun Bong
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530335/
https://ncbi.nlm.nih.gov/pubmed/27856432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2016-210310
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