Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases

OBJECTIVES: Juvenile idiopathic arthritis (JIA) is a heterogeneous group of diseases, comprising seven categories. Genetic data could potentially be used to help redefine JIA categories and improve the current classification system. The human leucocyte antigen (HLA) region is strongly associated wit...

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Bibliografiske detaljer
Udgivet i:Ann Rheum Dis
Main Authors: Hinks, A, Bowes, J, Cobb, J, Ainsworth, H C, Marion, M C, Comeau, M E, Sudman, M, Han, B, Becker, M L, Bohnsack, J F, de Bakker, P I W, Haas, J P, Hazen, M, Lovell, D J, Nigrovic, P A, Nordal, E, Punnaro, M, Rosenberg, A M, Rygg, M, Smith, S L, Wise, C A, Videm, V, Wedderburn, L R, Yarwood, A, Yeung, R S M, Prahalad, S, Langefeld, C D, Raychaudhuri, S, Thompson, S D, Thomson, W
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2017
Fag:
Basic and Translational Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530326/
https://ncbi.nlm.nih.gov/pubmed/27998952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2016-210025
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