Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25-dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (SPP-1 or osteopontin) gene expression.

Secreted phosphoprotein 1 (Spp-1; osteopontin) is one of the abundant noncollagenous proteins in bone matrix and is produced by osteoblasts. We examined the promoter region of the mouse Spp-1 gene and identified a sequence responsible for 1,25-dihydroxyvitamin D3 enhancement of the Spp-1 gene expres...

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Autori principali: Noda, M, Vogel, R L, Craig, A M, Prahl, J, DeLuca, H F, Denhardt, D T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC55301/
https://ncbi.nlm.nih.gov/pubmed/2175918
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