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Coordinate occupancy of AP-1 sites in the vitamin D-responsive and CCAAT box elements by Fos-Jun in the osteocalcin gene: model for phenotype suppression of transcription.

Osteocalcin, a bone-specific protein and marker of the mature osteoblast, is expressed only in nonproliferating osteoblasts in a mineralizing extracellular matrix, while type I collagen is expressed in proliferating cells. The nuclear proteins encoded by the c-fos and c-jun protooncogenes are expres...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Owen, T A, Bortell, R, Yocum, S A, Smock, S L, Zhang, M, Abate, C, Shalhoub, V, Aronin, N, Wright, K L, van Wijnen, A J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55300/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2124710/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.24.9990
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