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RNA polymerase involvement in the regulation of expression of Salmonella typhimurium pyr genes. Isolation and characterization of a fluorouracil-resistant mutant with high, constitutive expression of the pyrB and pyrE genes due to a mutation in rpoBC.

A mutant of Salmonella typhimurium with a defect in the regulation of pyr-gene expression was obtained during a selection for mutants resistant to a combination of the two pyrimidine analogs, 5-fluorouracil and 5-fluorouridine. The mutant possesses 4-fold elevated pools of the pyrimidine nucleoside...

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Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Jensen, K F, Neuhard, J, Schack, L
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1982
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552997/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6765170/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1982.tb01126.x
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