Poly (ADP-ribose) polymerase-1 inhibition decreases proliferation through G2/M arrest in esophageal squamous cell carcinoma

Poly (ADP-ribose) polymerase-1 (PARP1) plays a vital role in DNA repair and is expected to be an effective target in various malignancies. The aim of the present study was to investigate the clinical and biological significance of PARP1 expression in esophageal squamous cell carcinoma (ESCC). Immuno...

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Udgivet i:Oncol Lett
Main Authors: Yamamoto, Masaaki, Yamasaki, Makoto, Tsukao, Yukiko, Tanaka, Koji, Miyazaki, Yasuhiro, Makino, Tomoki, Takahashi, Tsuyoshi, Kurokawa, Yukinori, Nakajima, Kiyokazu, Takiguchi, Shuji, Mori, Masaki, Doki, Yuichiro
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529935/
https://ncbi.nlm.nih.gov/pubmed/28789382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6334
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