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Treatment with a JNK inhibitor increases, whereas treatment with a p38 inhibitor decreases, H(2)O(2)-induced calf pulmonary arterial endothelial cell death
Oxidative stress induces apoptosis in endothelial cells (ECs). Reactive oxygen species (ROS) promote cell death by regulating the activity of various mitogen-activated protein kinases (MAPKs) in ECs. The present study investigated the effects of MAPK inhibitors on cell survival and glutathione (GSH)...
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| Publicado no: | Oncol Lett |
|---|---|
| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5529758/ https://ncbi.nlm.nih.gov/pubmed/28789403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6330 |
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