Ginkgolide B Suppresses TLR4-Mediated Inflammatory Response by Inhibiting the Phosphorylation of JAK2/STAT3 and p38 MAPK in High Glucose-Treated HUVECs

AIM: Ginkgolide B is a Ginkgo biloba leaf extract that has been identified as a natural platelet-activating factor receptor (PAFR) antagonist. We investigated the effect of ginkgolide B on high glucose-induced TLR4 activation in human umbilical vein endothelial cells (HUVECs). METHODS: Protein expre...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Chen, Kun, Sun, Wenjia, Jiang, Yun, Chen, Beidong, Zhao, Yanyang, Sun, Jie, Gong, Huan, Qi, Ruomei
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529656/
https://ncbi.nlm.nih.gov/pubmed/28785380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9371602
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