JMJD3 and NF-κB-dependent activation of Notch1 gene is required for keratinocyte migration during skin wound healing

It has been shown that epigenetic regulation plays an important role in skin wound healing. We previously found that histone H3K27me3 demethylase JMJD3 regulates inflammation and cell migration in keratinocyte wound healing. In this study, we identified Notch1 as a direct target of JMJD3 and NF-κB i...

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Vydáno v:Sci Rep
Hlavní autoři: Na, Jungtae, Shin, Jee Yoon, Jeong, Hayan, Lee, Jee Youn, Kim, Beom Joon, Kim, Won Sun, Yune, Tae Young, Ju, Bong-Gun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529578/
https://ncbi.nlm.nih.gov/pubmed/28747631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06750-7
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