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Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis

Of the over 200 identified mammalian microRNAs (miRNAs), only a few have known biological activity. To gain a better understanding of the role that miRNAs play in specific cellular pathways, we utilized antisense molecules to inhibit miRNA activity. We used miRNA inhibitors targeting miR-23, 21, 15a...

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Autors principals: Cheng, Angie M., Byrom, Mike W., Shelton, Jeffrey, Ford, Lance P.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC552951/
https://ncbi.nlm.nih.gov/pubmed/15741182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki200
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