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Downregulation of Interferon-β and Inhibition of TLR3 Expression are associated with Fatal Outcome of Severe Fever with Thrombocytopenia Syndrome

Severe Fever with Thrombocytopenia Syndrome (SFTS) is an emerging infectious disease with high mortality and increasing prevalence in the East Asia. Though the etiological agent has been identified as a novel Bunyavirus, cellular mechanisms of viral pathogenesis and host immune response to SFTS viru...

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Publicado no:Sci Rep
Main Authors: Song, Peixin, Zheng, Nan, Zhang, Li, Liu, Yong, Chen, Taoyu, Bao, Changjun, Li, Zhifeng, Yong, Wei, Zhang, Yongyang, Wu, Chao, Wu, Zhiwei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529500/
https://ncbi.nlm.nih.gov/pubmed/28747721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06921-6
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