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4-dimensional functional profiling in the convulsant-treated larval zebrafish brain

Functional neuroimaging, using genetically-encoded Ca(2+) sensors in larval zebrafish, offers a powerful combination of high spatiotemporal resolution and higher vertebrate relevance for quantitative neuropharmacological profiling. Here we use zebrafish larvae with pan-neuronal expression of GCaMP6s...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Winter, Matthew J., Windell, Dylan, Metz, Jeremy, Matthews, Peter, Pinion, Joe, Brown, Jonathan T., Hetheridge, Malcolm J., Ball, Jonathan S., Owen, Stewart F., Redfern, Will S., Moger, Julian, Randall, Andrew D., Tyler, Charles R.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529444/
https://ncbi.nlm.nih.gov/pubmed/28747660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06646-6
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