ATP-dependent modulation of MgtE in Mg(2+) homeostasis

Magnesium is an essential ion for numerous physiological processes. MgtE is a Mg(2+) selective channel involved in the maintenance of intracellular Mg(2+) homeostasis, whose gating is regulated by intracellular Mg(2+) levels. Here, we report that ATP binds to MgtE, regulating its Mg(2+)-dependent ga...

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izdano v:Nat Commun
Main Authors: Tomita, Atsuhiro, Zhang, Mingfeng, Jin, Fei, Zhuang, Wenhui, Takeda, Hironori, Maruyama, Tatsuro, Osawa, Masanori, Hashimoto, Ken-ichi, Kawasaki, Hisashi, Ito, Koichi, Dohmae, Naoshi, Ishitani, Ryuichiro, Shimada, Ichio, Yan, Zhiqiang, Hattori, Motoyuki, Nureki, Osamu
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529423/
https://ncbi.nlm.nih.gov/pubmed/28747715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00082-w
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