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Striatal Network Models of Huntington's Disease Dysfunction Phenotypes

We present a network model of striatum, which generates “winnerless” dynamics typical for a network of sparse, unidirectionally connected inhibitory units. We observe that these dynamics, while interesting and a good match to normal striatal electrophysiological recordings, are fragile. Specifically...

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Bibliografske podrobnosti
izdano v:Front Comput Neurosci
Main Authors: Zheng, Pengsheng, Kozloski, James
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529396/
https://ncbi.nlm.nih.gov/pubmed/28798680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncom.2017.00070
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