The anti-cancer effects of itraconazole in epithelial ovarian cancer

We assessed the anti-proliferative activity of itraconazole using an EOC cell line (SKOV3ip1) and endothelial cell lines (HUVEC & SVEC4-10). We also examined angiogenesis (VEGFR2, p-ERK, p-PLCr1/2), hedgehog (Gli1, Ptch1, SMO), and mTOR (pS6K1) signaling pathways to determine the mechanism of ac...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Choi, Chel Hun, Ryu, Ji-Yoon, Cho, Young-Jae, Jeon, Hye-Kyung, Choi, Jung-Joo, Ylaya, Kris, Lee, Yoo-Young, Kim, Tae-Joong, Chung, Joon-Yong, Hewitt, Stephen M., Kim, Byoung-Gie, Bae, Duk-Soo, Lee, Jeong-Won
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529373/
https://ncbi.nlm.nih.gov/pubmed/28747628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06510-7
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi