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Thermodynamic Bounds on the Ultra- and Infra-affinity of Hsp70 for Its Substrates

The 70 kDa heat shock protein Hsp70 has several essential functions in living systems, such as protecting cells against protein aggregation, assisting protein folding, remodeling protein complexes, and driving translocation into organelles. These functions require high affinity for nonspecific amino...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Nguyen, Basile, Hartich, David, Seifert, Udo, Rios, Paolo De Los
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529314/
https://ncbi.nlm.nih.gov/pubmed/28746847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.010
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