Frequent mutation of the p53 gene in human esophageal cancer.

Sequence alterations in the p53 gene have been detected in human tumors of the brain, breast, lung, and colon, and it has been proposed that p53 mutations spanning a major portion of the coding region inactivate the tumor suppressor function of this gene. To our knowledge, neither transforming mutat...

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Bibliographic Details
Main Authors: Hollstein, M C, Metcalf, R A, Welsh, J A, Montesano, R, Harris, C C
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC55293/
https://ncbi.nlm.nih.gov/pubmed/2263646
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