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Sterol structure determines the separation of phases and the curvature of the liquid-ordered phase in model membranes

The existence of lipid rafts in biological membranes in vivo is still debated. In contrast, the formation of domains in model systems has been well documented. In giant unilamellar vesicles (GUVs) prepared from ternary mixtures of dioleoyl-phosphatidylcholine/sphingomyelin/cholesterol, a clear separ...

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Detalles Bibliográficos
Main Authors: Bacia, Kirsten, Schwille, Petra, Kurzchalia, Teymuras
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC552914/
https://ncbi.nlm.nih.gov/pubmed/15722414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408215102
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