High resolution molecular and histological analysis of renal disease progression in ZSF1 fa/fa(CP) rats, a model of type 2 diabetic nephropathy

ZSF1 rats exhibit spontaneous nephropathy secondary to obesity, hypertension, and diabetes, and have gained interest as a model system with potentially high translational value to progressive human disease. To thoroughly characterize this model, and to better understand how closely it recapitulates...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dower, Ken, Zhao, Shanrong, Schlerman, Franklin J., Savary, Leigh, Campanholle, Gabriela, Johnson, Bryce G., Xi, Li, Nguyen, Vuong, Zhan, Yutian, Lech, Matthew P., Wang, Ju, Nie, Qing, Karsdal, Morten A., Genovese, Federica, Boucher, Germaine, Brown, Thomas P., Zhang, Baohong, Homer, Bruce L., Martinez, Robert V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529026/
https://ncbi.nlm.nih.gov/pubmed/28746409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181861
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