Cross-recognition of a pit viper (Crotalinae) polyspecific antivenom explored through high-density peptide microarray epitope mapping

Snakebite antivenom is a 120 years old invention based on polyclonal mixtures of antibodies purified from the blood of hyper-immunized animals. Knowledge on antibody recognition sites (epitopes) on snake venom proteins is limited, but may be used to provide molecular level explanations for antivenom...

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Udgivet i:PLoS Negl Trop Dis
Main Authors: Engmark, Mikael, Lomonte, Bruno, Gutiérrez, José María, Laustsen, Andreas H., De Masi, Federico, Andersen, Mikael R., Lund, Ole
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529020/
https://ncbi.nlm.nih.gov/pubmed/28708892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005768
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