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Tomosyn associates with secretory vesicles in neurons through its N- and C-terminal domains

The secretory pathway in neurons requires efficient targeting of cargos and regulatory proteins to their release sites. Tomosyn contributes to synapse function by regulating synaptic vesicle (SV) and dense-core vesicle (DCV) secretion. While there is large support for the presynaptic accumulation of...

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Publicado en:PLoS One
Autores principales: Geerts, Cornelia J., Mancini, Roberta, Chen, Ning, Koopmans, Frank T. W., Li, Ka Wan, Smit, August B., van Weering, Jan R. T., Verhage, Matthijs, Groffen, Alexander J. A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529015/
https://ncbi.nlm.nih.gov/pubmed/28746398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180912
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