Yeast-expressed recombinant As16 protects mice against Ascaris suum infection through induction of a Th2-skewed immune response

BACKGROUND: Ascariasis remains the most common helminth infection in humans. As an alternative or complementary approach to global deworming, a pan-anthelminthic vaccine is under development targeting Ascaris, hookworm, and Trichuris infections. As16 and As14 have previously been described as two ge...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Wei, Junfei, Versteeg, Leroy, Liu, Zhuyun, Keegan, Brian, Gazzinelli-Guimarães, Ana Clara, Fujiwara, Ricardo T., Briggs, Neima, Jones, Kathryn M., Strych, Ulrich, Beaumier, Coreen M., Bottazzi, Maria Elena, Hotez, Peter J., Zhan, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529013/
https://ncbi.nlm.nih.gov/pubmed/28708895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005769
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