Genome‐wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis

Background: DNA methylation alterations are early events in tumorigenesis and important in the regulation of gene expression in cancer cells. Lung cancer patients have in general a poor prognosis, and a deeper insight into the epigenetic landscape in lung adenocarcinoma tumors and its prognostic imp...

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Détails bibliographiques
Publié dans:Mol Oncol
Auteurs principaux: Bjaanæs, Maria Moksnes, Fleischer, Thomas, Halvorsen, Ann Rita, Daunay, Antoine, Busato, Florence, Solberg, Steinar, Jørgensen, Lars, Kure, Elin, Edvardsen, Hege, Børresen-Dale, Anne-Lise, Brustugun, Odd Terje, Tost, Jörg, Kristensen, Vessela, Helland, Åslaug
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528958/
https://ncbi.nlm.nih.gov/pubmed/26601720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.10.021
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