Conversion to stem‐cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells

Cancer cells within a tumor are functionally heterogeneous and specific subpopulations, defined as cancer initiating cells (CICs), are endowed with higher tumor forming potential. The CIC state, however, is not hierarchically stable and conversion of non‐CICs to CICs under microenvironment signals m...

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Bibliographic Details
Published in:Mol Oncol
Main Authors: Andriani, Francesca, Bertolini, Giulia, Facchinetti, Federica, Baldoli, Erika, Moro, Massimo, Casalini, Patrizia, Caserini, Roberto, Milione, Massimo, Leone, Giorgia, Pelosi, Giuseppe, Pastorino, Ugo, Sozzi, Gabriella, Roz, Luca
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528953/
https://ncbi.nlm.nih.gov/pubmed/26514616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.10.002
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