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Negative immune checkpoints on T lymphocytes and their relevance to cancer immunotherapy
The term ‘inhibitory checkpoint’ refers to the broad spectrum of co‐receptors expressed by T cells that negatively regulate T cell activation thus playing a crucial role in maintaining peripheral self‐tolerance. Co‐inhibitory receptor ligands are highly expressed by a variety of malignancies allowin...
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| Publicado en: | Mol Oncol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528732/ https://ncbi.nlm.nih.gov/pubmed/26578451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.10.008 |
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