Enhanced expression of retinoic acid receptor alpha (RARA) induces epithelial‐to‐mesenchymal transition and disruption of mammary acinar structures

The early steps of mammary tumorigenesis include loss of epithelial cell polarity, escape from anoikis, and acquisition of proliferative capacity. The genes responsible for these processes are predicted to be early diagnostic markers or new therapeutic targets. Here we tested 51 genes coamplified wi...

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Publicat a:Mol Oncol
Autors principals: Doi, Ayano, Ishikawa, Kosuke, Shibata, Nao, Ito, Emi, Fujimoto, Jiro, Yamamoto, Mizuki, Shiga, Hatsuki, Mochizuki, Hiromi, Kawamura, Yoshifumi, Goshima, Naoki, Semba, Kentaro, Watanabe, Shinya
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2014
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528664/
https://ncbi.nlm.nih.gov/pubmed/25300573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.09.005
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